It is also estimated that in Mexico 8% of people over 65 years of age might have some form of cognitive impairment. ConclusionesĮl MoCA-E es un instrumento con validez y confiabilidad para el cribado de DCL y demencia en la población mexicana, aun después de ajustar por edad y escolaridad.Ĭognitive impairment is a significant cause of morbidity and mortality associated with population ageing worldwide, including in developing countries like Mexico, 1 where the annual incidence of dementia in the over 65 s is 30. La regresión multinomial no mostró asociación con la escolaridad y la edad tanto para DCL como para demencia. Para demencia, la sensibilidad fue del 98% y la especificidad, del 93% con el punto de corte de 24puntos (área bajo la curva = 0,998 p < 0,001). La sensibilidad fue del 80% y la especificidad, del 75% con el punto de corte de 26 puntos para DCL (área bajo la curva = 0,886 p < 0,001). La confiabilidad del MoCA-E fue 0,89 con un coeficiente de correlación intraclase de 0,955. ResultadosĮl promedio de edad de los participantes era 76 ± 8,1 años la tasa de escolaridad, 10,7 ± 5,2. Se construyeron curvas ROC y un modelo de regresión multinomial para evaluar el efecto de la edad y la escolaridad en el desempeño del MOCA-E. Se aplicó el MoCA-E y el Mini- Mental State Evaluation al inicio y en los últimos meses, para establecer la confiabilidad intraobservador. Se incluyó a 168 participantes en una clínica de memoria de la ciudad de México, en 3 grupos: 59 cognitivamente sanos (GCS), 52 con DCL (criterios del DSM- V) y 57 con demencia (criterios NINCDS-ADRDA). The MoCA-S is a valid and reliable instrument for MCI and dementia screening in the Mexican population, even after adjusting for age and education.Įstablecer la validez y confiabilidad del Montreal Evaluación Cognitiva en Español (MoCA-E) para identificar deterioro cognitivo leve (DCL) y demencia en adultos mayores mexicanos. The multinomial regression showed no association with education and age for both the MCI and dementia groups. For the dementia group, the sensitivity was 98% and specificity was 93%, with a cut-off point of 24 points (area under the curve, 0.998 p < 0.001). Sensitivity was 80% and specificity was 75%, with a cut-off point of 26 points for MCI (area under the curve, 0.886 p < 0.001). The reliability of the MoCA-S was 0.89 and the intraclass correlation coefficient was 0.955. The mean age of the participants was 76 ± 8.1 years and the education rate was 10.7 ± 5.2. ROC curves and a multinomial regression model were constructed to evaluate the effect of age and education on MoCA-S performance. The MoCA-S and Mini-Mental State Evaluation (MMSE) were applied at baseline and during the last months to establish intra-observer reliability. Material and methodsġ68 participants from a memory clinic in Mexico City were enrolled and divided into 3 groups: 59 cognitively healthy (CHG), 52 with mild cognitive impairment (MCI) (DSM-5 criteria) and 57 with dementia (NINCDS-ADRDA criteria). The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE.To establish the validity and reliability of the Montreal Cognitive Assessment in Spanish (MoCA-S) to identify mild cognitive impairment (MCI) and dementia in the Mexican elderly population. MCI as an entity is evolving and somewhat controversial. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively). In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD. Ninety-four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini-Mental State Examination (MMSE) score > or =17), and 90 healthy elderly controls (NC). To develop a 10-minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first-line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia.Ī community clinic and an academic center.
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